Marie Caudill, Ph.D., RD

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Marie Caudill, Ph.D., RD

Dr. Caudill reviews the functions of choline, her research on choline as an essential nutrient, particularly as this relates to pregnant women, and dietary sources of choline.

Representative Publications as of October 2010

1. Caudill MA. Pre- and Postnatal Health: Evidence of Increased Choline Needs. J Am Diet Assoc. 2010;110:1198-1206.

2. Caudill MA. Folate bioavailability: Implications for establishing dietary recommendations and optimizing status. Am J Clin Nutr 2010;91(suppl):1455S-60S. doi: 10.3945/ajcn.2010.28674E.

3. Kathirvel E, Morgan K, Caudill MA, Nandgiri G,Sandoval BC, Bottiglieri T, French SW,Morgan TR. Betaine improves non alcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine. Am J Physiol. 2010 Aug 19. [Epub ahead of print]

4. Shin W, Yan J, Abratte CF, Vermeylen F, and Caudill MA. Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic sub-group of folate-compromised men. J Nutr. 2010; 140:975-980.

5. Chan J, Deng L, Pickell L, Wu Q, Yan J, Caudill MA, Rozen R. Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice. Am J Clin Nutr 2010;91:1035–43.

6. Caudill MA, Dellschaft N, Solis C, Hinkis S, Ivanov AA, Nash-Barboza S, Randall KE, Jackson B, Solomita GN, Vermeylen F. Choline intake, plasma riboflavin and the PEMT G5465A genotype predict plasma homocysteine in folate deplete Mexican American men with the MTHFR 677TT genotype. J Nutr. 2009;139:727-733

7. Ivanov A, Nash-Barboza S, Hinkis S, Caudill MA. Genetic variants in phosphatidylethanolamine N-methyltransferase (PEMT) and methylenetetrahydrofolate dehydrogenase (MTHFD1) influence biomarkers of choline metabolism when folate intake is restricted. J Amer Diet Assoc. 2009;109:313-318.

8. Abratte CM, Wang W, Li R, Axume J, Moriarty DJ, Caudill MA. Choline status is not a reliable indicator of moderate changes in dietary choline consumption in pre-menopausal women. J Nutr Biochem. 2008;20:62–69.

9. Veenema K, Solis C, Li R, Wang W, Maletz CV, Abratte C, Caudill MA. Choline intakes at AI levels are sufficient in preventing liver dysfunction in Mexican American men but are not optimal in minimizing plasma total homocysteine increases after a methionine load. Am J Clin Nutr. 2008;88:685-92.

10. Hung J, Abratte CM, Wang W, Li R, Moriarty DJ, Caudill MA. Ethnicity and folate intake influence choline status in young women consuming controlled nutrient intakes. J Am Coll Nutr. 2008;27:253-259.

11. Abratte CM, Wang W, Li R, Moriarty DJ, Caudill MA. Folate intake and the MTHFR C677T genotype influence choline status in young Mexican American women. J Nutr Biochem. 2008;19:158-165.

12. Solis C, Veenema K, Ivanov AA, Tran S, Wang W, Moriarty DJ, Maletz CV, Caudill MA. Folate intake at RDA levels is inadequate for Mexican American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr. 2008;138:1-6.

13. Axume J, Smith SS, Pogribny IP, Moriarty DJ, Caudill MA. The methylenetetrahydrofolate reductase (MTHFR) 677C?T polymorphism and folate interact to lower global leukocyte DNA methylation in young Mexican American women. Nutr Res. 2007;27:13-17.

14. Vakili S, Caudill MA. Personalized Nutrition: Nutritional Genomics as a Potential Tool for Targeted Medical Nutrition Therapy. Nutrition Reviews. 2007;65:301-315.

15. McCabe DC, Caudill MA. DNA methylation, genomic silencing, and links to nutrition and cancer. Nutrition Reviews. 2005;63:183-195.

16. Yang TL, Hung J, Caudill MA, Urrutia TF, Alamilla A, Perry CA, Li R, Hata H, Cogger EA. A long-term controlled folate feeding study in young women supports the validity of the 1.7 multiplier in the dietary folate equivalency equation. J Nutr. 2005;135: 1139-1145.

17. Perry C., Renna S., Khitun E., Ortiz, M., Moriarty D. and Caudill MA. Ethnicity and race influences folate status response to controlled folate intakes in non-pregnant young women. J Nutr. 2004;134:1786-1792

18. Caudill MA. The role of folate in reducing chronic and developmental disease risk: an overview. Journal of Food Science. 2004;69:SNQ55-67.

19. Guinotte C, Axume J, Hata Hiroko, Urrutia T, Burns M, Alamilla A, McCabe D, Singgih A., Cogger EA and Caudill MA. Methylenetetrahydrofolate reductase C677T variant modulates folate status response to controlled folate intakes in young women. J Nutr. 2003;133:1272-1280.

20. Torabian Esfahani S, Cogger EA and Caudill MA. Heterogeneity in MTHFR C677T and A1298C genotypes among women differing in ethnicity. J Am Diet Assoc. 2003;103:200-207.

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